Reduction of polyovular follicles and polynuclear ova by estradiol monobenzoate
Reduction of polyovular follicles and polynuclear ova by estradiol monobenzoate
复制标题
单苯甲酸雌二醇减少多卵泡和多核卵
DOI：
10.1002/ar.1091340308
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发表时间：
1959
期刊：
影响因子：
--
通讯作者：
H. A. Kent
中科院分区：
文献类型：
--
作者：
H. A. Kent
The widespread occurrence of polyovular follicles and polynuclear ova among mammals is indicated by the reports of Hartman ( '26)' Lane ( '38)' Davis and Hall ( '50), and Pawson ( '51). The aberrant forms are more common in immature animals but are also present in older individuals. Attempts to explain the occurrence of these two types of abnormalities have been largely based on morphological evidence and the possibility of a sequential relationship between them, rather than on a viewpoint which regards them as part of the general problem of control of ovarian function. It is now generally agreed that control of follicular development is exercised both by the pituitary through its production of gonadotropins (Adams, '53) and secondarily through production of estrogens by the theca interna of the ovary (Hisaw, '47). The following work was undertaken to determine whether or not the administration of estrogen (reported by Payne and Hellbaum ('55) to be capable of supporting normal follicular maturation in the absence of the pituitary) would also reduce the number of polyovular follicles and polynuclear ova.
