Comorbidities, mortality and causes of death among patients with tuberculosis in Denmark 1998-2010: a nationwide, register-based case-control study

Comorbidities, mortality and causes of death among patients with tuberculosis in Denmark 1998-2010: a nationwide, register-based case-control study
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DOI:
10.1136/thoraxjnl-2016-209240
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发表时间:
2018-01-01
期刊:
影响因子:
10
通讯作者:
Lokke, Anders
Lokke, Anders
中科院分区:
医学1区
文献类型:
--
作者:
Floe, Andreas;Hilberg, Ole;Lokke, Anders

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目的评估合并症、年龄和结核病临床表现对丹麦结核病患者死亡率的影响。方法在1998-2010年诊断为结核病的ICD-10(国际疾病和相关健康问题统计分类第10次修订)丹麦患者在国家患者登记处被确定,并与对照组(1:4)在年龄、性别、婚姻状况和地理位置上匹配。结果共纳入8433例结核病患者和33707例健康对照者。呼吸系统疾病是病例组最常见的合并症(病例组12.4%,对照组3.8%(P
Objective To evaluate the impact of comorbidities, age and clinical presentation of TB on mortality among Danish patients with TB.Methods Danish patients with an ICD-10 (International Statistical Classification of Diseases and Related Health Problems 10th Revision) diagnosis of TB in 1998-2010 were identified in the National Patient Registry and matched with controls (1:4) on age, gender, civil status and geography. Comorbid diagnoses up to 3 years before and after TB diagnosis or enrolment as control as well as survival data were obtained from national databasesResults We included 8433 cases and 33 707 controls. Respiratory diseases were the most common comorbidities among cases (12.4% of cases, 3.8% of controls (p