Proton-Conductive Gas Sensor: a New Way to Realize Highly Selective Ammonia Detection for Analysis of Exhaled Human Breath
Proton-Conductive Gas Sensor: a New Way to Realize Highly Selective Ammonia Detection for Analysis of Exhaled Human Breath
复制标题
质子传导气体传感器：实现高选择性氨检测分析人体呼出气体的新方法
DOI：
10.1021/acssensors.9b01763
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发表时间：
2020
期刊：
影响因子：
8.9
通讯作者：
Zhang Tong
中科院分区：
文献类型：
--
作者：
Zhao Hongran;Liu Lichao;Lin Xiuzhu;Dai Jianxun;Liu Sen;Fei Teng;Zhang Tong
呼出气的分析对于早期无创诊断具有重要意义。选择性差和强湿度是制约气体传感器应用于呼出气分析的两个瓶颈。在这项工作中，我们利用吸附，溶解，电离和迁移过程中的氨在湿非共轭亲水聚合物，实现有效的氨检测。呼出气中不可缺少的高湿度气氛变成了氨传感的有利条件。非共轭聚合物传感器可以区分氨从大多数其他气体，因为它的极高的溶解度和良好的电离能力。基于聚（乙烯基吡咯烷酮）（PVP）的传感器可以检测0.5 ppm的氨具有极高的选择性。通过复阻抗图（CIP）和石英晶体微天平（QCM）测量，对氨传感机理进行了深入研究。最后，在模拟环境中评估PVP传感器用于呼出气中氨检测的潜力。
The analysis of exhaled human breath has great significance for early noninvasive diagnosis. Poor selectivity and strong humidity are two bottlenecks for the application of gas sensors to exhaled breath analysis. In this work, we utilized the adsorption, dissolution, ionization, and migration processes of ammonia in wet nonconjugated hydrophilic polymers to realize effective ammonia detection. The indispensable high-humidity atmosphere of exhaled breath was turned into a favorable condition for ammonia sensing. Nonconjugated polymer sensors can distinguish ammonia from most other gases because of its extremely high solubility and good ionization ability. A sensor based on poly(vinyl pyrrolidone) (PVP) could detect 0.5 ppm ammonia with an extremely high selectivity. The ammonia-sensing mechanism was thoroughly investigated by complex impedance plots (CIPs) and a quartz crystal microbalance (QCM) measurement. Finally, the potential of the PVP sensor for ammonia detection in exhaled breath was evaluated in simulated environments.