Antibacterial Activities Effectuated by Co-continuous Epoxy-based Polymer Materials
Antibacterial Activities Effectuated by Co-continuous Epoxy-based Polymer Materials
复制标题
共连续环氧基聚合物材料的抗菌活性
DOI：
10.1016/j.colsurfb.2013.01.043
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
K. Hosoya
中科院分区：
文献类型：
--
作者：
T. Kubo;K. Yasuda;Y. Tominaga;K. Otsuka;K. Hosoya
我们报告了具有大孔共连续结构以及疏水和/或亲水表面的基于环氧树脂的整体介质（环氧整体）的抗菌活性。利用含有铵基团的环氧整料，使用大肠杆菌进行抗菌实验。结果表明，用含氮环氧单体制备的整体介质明显显示出抗菌活性，而用不含氮原子的单体制备的整体介质显示出较低的抗菌活性。此外，季铵化的环氧聚合物表现出显著的抗菌活性。进一步的研究表明，观察到的抗菌活性涉及基于溶液pH值变化和季铵疏水相互作用的急剧效应。
We report antibacterial activities of the epoxy-resin-based monolithic media (epoxy monoliths) having macroporous co-continuous structure as well as hydrophobic and/or hydrophilic surface. Utilizing epoxy monoliths containing ammonium groups, the antibacterial experiments were examined using Escherichia coli. As the results, the monolithic media prepared with an epoxy monomer having nitrogen atoms clearly showed antibacterial activities, while those prepared using the monomer without nitrogen atom showed less antibacterial activities. Additionally, the quaternization of the epoxy polymers were expressed significant antibacterial activities. Further studies elucidated that the observed antibacterial activities involved the steep effect based on pH changing of solution and hydrophobic interactions by the quaternary ammonium.