Incidence of Clinician-Diagnosed Lyme Disease, United States, 2005-2010.
Incidence of Clinician-Diagnosed Lyme Disease, United States, 2005-2010.
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DOI：
10.3201/eid2109.150417
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发表时间：
2015-09
影响因子：
11.8
通讯作者：
Mead PS
中科院分区：
文献类型：
--
作者：
Nelson CA;Saha S;Kugeler KJ;Delorey MJ;Shankar MB;Hinckley AF;Mead PS
从一个大型医疗索赔数据库推断，每年发生329 000例。国家监测提供了关于莱姆病（LD）的重要信息，但在实践中存在报告不足和差异。来自其他来源的关于LD的全国流行病学的信息是有限的。回顾性分析了2005-2010年全国健康保险索赔数据库，使用国际疾病分类第九次修订版、临床修改、代码和抗菌药物处方确定了临床诊断为LD的患者。在103，647，966人年中，确定了985例住院和44，445例门诊LD诊断。流行病学模式总体上与美国监测数据相似。5-9岁男孩和60-64岁男女的门诊发病率最高。根据外推至美国人群并应用编码校正因子，我们估计年发病率为106.6例/100，000人，每年发生1329，000例（95%可信区间296，000 - 376，000）LD病例。LD是美国一个主要的公共卫生问题，导致大量使用卫生保健资源。
Extrapolation from a large medical claims database suggests that 329,000 cases occur annually. National surveillance provides important information about Lyme disease (LD) but is subject to underreporting and variations in practice. Information is limited about the national epidemiology of LD from other sources. Retrospective analysis of a nationwide health insurance claims database identified patients from 2005–2010 with clinician-diagnosed LD using International Classification of Diseases, Ninth Revision, Clinical Modification, codes and antimicrobial drug prescriptions. Of 103,647,966 person-years, 985 inpatient admissions and 44,445 outpatient LD diagnoses were identified. Epidemiologic patterns were similar to US surveillance data overall. Outpatient incidence was highest among boys 5–9 years of age and persons of both sexes 60–64 years of age. On the basis of extrapolation to the US population and application of correction factors for coding, we estimate that annual incidence is 106.6 cases/100,000 persons and that ≈329,000 (95% credible interval 296,000–376,000) LD cases occur annually. LD is a major US public health problem that causes substantial use of health care resources.