RANDOMIZED TRIAL OF ENDOSCOPIC ENDOPROSTHESIS VERSUS OPERATIVE BYPASS IN MALIGNANT OBSTRUCTIVE-JAUNDICE
RANDOMIZED TRIAL OF ENDOSCOPIC ENDOPROSTHESIS VERSUS OPERATIVE BYPASS IN MALIGNANT OBSTRUCTIVE-JAUNDICE
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DOI：
10.1136/gut.30.8.1132
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发表时间：
1989-08-01
期刊：
影响因子：
24.5
通讯作者：
MATZEN, P
中科院分区：
文献类型：
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作者：
ANDERSEN, JR;SORENSEN, SM;MATZEN, P
在肝外胆管恶性狭窄引起的梗阻性黄疸患者中，我们比较了经内镜内支架或旁路手术缓解后的生存时间、并发症发生率、住院要求和生活质量。在诊断性内镜胆管造影期间，50例患者被随机分配至两种治疗方案。所有25例随机分配至内假体组的患者均接受了该手术治疗，而25例随机分配至旁路手术组的患者中仅19例接受了胆消化道吻合术。生命表分析显示，治疗组或随机化组之间的生存期无差异。当比较其他变量时，没有发现差异。我们得出的结论是，通过内窥镜引入内假体来缓解恶性胆管阻塞的阻塞性黄疸与手术旁路一样有效。
In patients with obstructive jaundice caused by malignant stricture of the extrahepatic bile duct we compared survival time, complication rates, hospitalisation requirements, and quality of life after palliation by endoscopic endoprosthesis or bypass surgery. During diagnostic endoscopic cholangiography 50 patients were randomised to the two treatment alternatives. All 25 patients randomised to endoprosthesis were treated by this procedure, whereas only 19 of 25 patients randomised to bypass surgery underwent operative biliary-digestive anastomosis. Life table analysis revealed no difference in survival between treatment groups or randomisation groups. No differences were found when other variables were compared. We conclude, that palliation of obstructive jaundice in malignant bile duct obstruction with endoscopically introduced endoprosthesis is as effective as operative bypass.