Selection for cognitive control: A functional magnetic resonance imaging study on the selection of task-relevant information
Selection for cognitive control: A functional magnetic resonance imaging study on the selection of task-relevant information
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DOI：
10.1523/jneurosci.2513-04.2004
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发表时间：
2004-10-06
影响因子：
5.3
通讯作者：
von Cramon, DY
中科院分区：
文献类型：
--
作者：
Brass, M;von Cramon, DY
我们生活在复杂的环境中，有必要不断可靠地区分相关和无关的信息。本研究的目的是调查任务相关信息选择的神经基础。我们设计了一个新的范式，参与者必须在两个不同的任务之间切换，这两个任务由任务线索指示。任务线索有相关线索维度和不相关线索维度。在一致性实验中，两个线索维度表示相同的任务；在不一致性实验中，它们表示不同的任务；在中性实验中，只有相关维度表示任务。通过比较两个线索维度都是信息量的试验(一致和不一致试验)和只有相关维度是信息量的试验(中性试验)，我们能够表明外侧前额叶皮质和顶沟中的一个区域参与了任务相关信息的选择。此外，目前的范式允许调查所选任务和刺激维度的影响。在前额叶皮质中没有发现显著的影响，表明该区域在任务相关信息的选择中起着非常抽象的作用。
The complex environment we live in makes it necessary to distinguish relevant from irrelevant information constantly and reliably. The aim of the present study was to investigate the neural substrate underlying the selection of task-relevant information. We devised a new paradigm in which participants had to switch between two different tasks that were instructed by task cues. The task cues had a relevant and an irrelevant cue dimension. In congruent trials, both cue dimensions indicated the same task; in incongruent trials, they indicated different tasks; and in neutral trials, only the relevant dimension indicated a task. By comparing trials in which both cue dimensions were informative (congruent and incongruent trials) with trials in which only the relevant dimension was informative (neutral trials), we were able to show that the lateral prefrontal cortex and a region in the intraparietal sulcus are involved in the selection of task-relevant information. Furthermore, the present paradigm allows the influence of the selected task and stimulus dimension to be investigated. No significant influence was found in the prefrontal cortex, indicating that this region serves a very abstract role in the selection of task-relevant information.