Characterization of TolC Efflux Pump Proteins from Pasteurella multocida
Characterization of TolC Efflux Pump Proteins from Pasteurella multocida
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DOI：
10.1128/aac.00245-08
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发表时间：
2008-11-01
影响因子：
4.9
通讯作者：
Adler, Ben
中科院分区：
文献类型：
--
作者：
Hatfaludi, Tamas;Al-Hasani, Keith;Adler, Ben
鉴定出多杀性巴氏杆菌的两个TolC同源物PM0527和PM1980。一个pm0527突变体对一系列化学物质的敏感性增加，包括利福平(512倍)和吖啶橙(128倍)。一个pm1980突变体对利福平、头孢他啶和万古霉素的敏感性增加。
Two TolC homologs, PM0527 and PM1980, were identified for Pasteurella multocida. A pm0527 mutant displayed increased susceptibility to a range of chemicals, including rifampin (512-fold) and acridine orange (128-fold). A pm1980 mutant showed increased susceptibility to rifampin, ceftazidime, and vancomycin.