COMPLEX PARTIAL SEIZURES OF INFANCY
COMPLEX PARTIAL SEIZURES OF INFANCY
复制标题
DOI：
10.1001/archneur.1987.00520210013011
复制
发表时间：
1987-09-01
影响因子：
--
通讯作者：
DUCHOWNY, MS
中科院分区：
文献类型：
--
作者：
DUCHOWNY, MS
先前尚未描述过婴儿期复杂部分性癫痫发作的发作表现。使用长期视频/脑电图和遥测监测技术，记录了 14 名 2 岁以下婴儿的 187 次癫痫发作。除一名例外，婴儿均因顽固性癫痫发作而严重延迟。计算机断层扫描显示九人的双侧明显异常。最常见的癫痫发作表现包括行为停止、头部和眼睛被迫侧偏以及上肢伸肌强直僵硬。咀嚼、吸吮、张嘴和眨眼等复杂的面部自动行为相对常见。脑电图显示，发作期阵发性发作总是偏侧，而发作间期记录显示多灶性癫痫放电、全身性减慢和电压衰减。发作期行为表现和电击模式非常独特，但在常规评估中常常未被诊断出来。
Ictal manifestations of complex partial seizures in infancy have not been described previously. Using long-term video/electroencephalographic and telemetric monitoring techniques, 187 seizures were recorded in 14 infants under 2 years of age. With one exception, the infants were profoundly delayed with intractable seizures. Nine had marked bilateral abnormalities on computed tomographic scan. The seizure manifestations noted most frequently consisted of behavioral arrest with forced lateralized deviation of the head and eyes and tonic upper-extremity extensor stiffening. Complex facial automatisms such as chewing, sucking, mouthing, and blinking were relatively common. Ictal paroxysmal onset was always lateralized on electroencephalograms, whereas the interictal recordings revealed multifocal epileptic discharges, generalized slowing, and voltage attenuation. The ictal behavioral manifestations and electric seizure patterns were quite distinctive yet were often undiagnosed on routine evaluations.