Establishing minimum clinically important difference values for the Patient-Reported Outcomes Measurement Information System Physical Function, hip disability and osteoarthritis outcome score for joint reconstruction, and knee injury and osteoarthritis outcome score for joint reconstruction in orthopaedics
Establishing minimum clinically important difference values for the Patient-Reported Outcomes Measurement Information System Physical Function, hip disability and osteoarthritis outcome score for joint reconstruction, and knee injury and osteoarthritis outcome score for joint reconstruction in orthopaedics
复制标题
DOI：
10.5312/wjo.v9.i3.41
复制
发表时间：
2018-03-18
影响因子：
1.9
通讯作者：
Saltzman, Charles L.
中科院分区：
文献类型：
--
作者：
Hung, Man;Bounsanga, Jerry;Saltzman, Charles L.
目的建立最小临床重要差异（MCID）的测量在骨科患者人群与关节disorders.METHODS18岁及以上的成年患者寻求照顾的关节条件在骨科诊所采取了病人报告的结果测量信息系统的身体功能（PROMIS（R）PF）计算机适应性测试（CAT），髋关节残疾和关节重建骨关节炎结局评分（HOOS JR），以及2014年2月至2017年4月的膝关节损伤和关节炎关节重建结局评分（KOOS JR）。MCID使用基于锚和基于分布的方法计算。患者报告的有意义的功能变化，因为他们的第一个诊所就诊被用作一个锚。有2226名患者参与，平均年龄为61.16岁（SD = 12.84），41.6%的男性，和89.7%的白人。PROMIS（R）PF CAT的平均变化范围为7.29 - 8.41，HOOS JR为14.81 - 19.68，KOOS JR为14.51 - 18.85。PF CAT的ROC临界值范围为1.97-8.18，HOOS JR为6.33-43.36，KOOS JR为2.21-8.16。基于分布的方法估计PROMIS（R）PF CAT的MCID值范围为2.45至21.55; HOOS JR为3.90至43.61，KOOS JR为3.98至40.67。范围内的中位MCID值与每项测量的平均变化评分相似，PF CAT为7.9，HOOS JR为18.0，KOOS JR为15.1。结论这是第一项综合研究，为患有关节疾病的骨科患者提供了PROMIS（R）PF、HOOS JR和KOOS JR的广泛MCID。
AIMTo establish minimum clinically important difference (MCID) for measurements in an orthopaedic patient population with joint disorders.METHODSAdult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS (R) PF) computerized adaptive test (CAT), hip disability and osteoarthritis outcome score for joint reconstruction (HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction (KOOS JR) from February 2014 to April 2017. MCIDs were calculated using anchorbased and distribution-based methods. Patient reports of meaningful change in function since their first clinic encounter were used as an anchor.RESULTSThere were 2226 patients who participated with a mean age of 61.16 (SD = 12.84) years, 41.6% male, and 89.7% Caucasian. Mean change ranged from 7.29 to 8.41 for the PROMIS (R) PF CAT, from 14.81 to 19.68 for the HOOS JR, and from 14.51 to 18.85 for the KOOS JR. ROC cut-offs ranged from 1.97-8.18 for the PF CAT, 6.33-43.36 for the HOOS JR, and 2.21-8.16 for the KOOS JR. Distribution-based methods estimated MCID values ranging from 2.45 to 21.55 for the PROMIS (R) PF CAT; from 3.90 to 43.61 for the HOOS JR, and from 3.98 to 40.67 for the KOOS JR. The median MCID value in the range was similar to the mean change score for each measure and was 7.9 for the PF CAT, 18.0 for the HOOS JR, and 15.1 for the KOOS JR.CONCLUSIONThis is the first comprehensive study providing a wide range of MCIDs for the PROMIS (R) PF, HOOS JR, and KOOS JR in orthopaedic patients with joint ailments.