Large-scale imaging in small brains.
Large-scale imaging in small brains.
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DOI：
10.1016/j.conb.2015.01.007
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发表时间：
2015-06
影响因子：
5.7
通讯作者：
Engert F
中科院分区：
文献类型：
--
作者：
Ahrens MB;Engert F
大脑中密集的连通性和细胞成回路的排列意味着一个神经元的活动可以影响许多其他神经元。为了全面观察这个相互联系的系统，神经科学的一个愿望是同时记录尽可能多的神经元。实现这一目标有两条有用的途径：一是扩大功能性成像技术的空间范围，二是利用大脑较小的动物。在这里，我们回顾了在小型脊椎动物和无脊椎动物中成像许多神经元和已识别的完整神经元群体的最新进展。
The dense connectivity in the brain and arrangements of cells into circuits means that one neuron’s activity can influence many others. To observe this interconnected system comprehensively, an aspiration within neuroscience is to record from as many neurons as possible at the same time. There are two useful routes toward this goal: one is to expand the spatial extent of functional imaging techniques, and the second is to use animals with small brains. Here we review recent progress toward imaging many neurons and complete populations of identified neurons in small vertebrates and invertebrates.