An event-related functional MRI study of the Stroop color word interference task
An event-related functional MRI study of the Stroop color word interference task
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DOI：
10.1093/cercor/10.6.552
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发表时间：
2000-06-01
期刊：
影响因子：
3.7
通讯作者：
Gore, JC
中科院分区：
文献类型：
--
作者：
Leung, HC;Skudlarski, P;Gore, JC
在这项研究中，我们试图定义的神经回路差异激活的认知干扰。我们使用事件相关功能磁共振成像（fMRI）来识别在两个实验中被Stroop单词颜色任务激活的大脑区域。在第一个实验中，我们使用不常见的，不一致的彩色单词刺激，引起强烈的Stroop干扰（“传统Stroop”范式）。在第二个实验中，我们使用不常见的，一致的彩色单词（“逆Stroop”范式），以确认在第一个实验中确定的区域实际上是专门相关的Stroop效应，而不是非特定的古怪的影响与使用不频繁的刺激。常规Stroop的表现特别激活了前扣带、前额叶、启动子和下额叶区域。在当前实验中，这些激活区域与使用更传统的区组设计的功能磁共振成像实验中激活的区域一致。最后，对fMRI信号变化的时程分析表明，这些激活区域的信号变化具有不同的起始和偏移。时间进程的结果表明，不同的脑区的行动可以暂时分离。
In this study we have attempted to define the neural circuits differentially activated by cognitive interference. We used event-related functional magnetic resonance imaging (fMRI) to identify areas of the brain that are activated by the Stroop word-color task in two experiments. In the first experiment, we used infrequent, incongruent colored word stimuli to elicit strong Stroop interference (the 'conventional Stroop' paradigm). In the second experiment, we used infrequent, congruent colored words (the 'inverse Stroop' paradigm) to confirm that the regions identified in the first experiment were in fact specifically related to the Stroop effect and not to nonspecific oddball effects associated with the use of infrequent stimuli. Performance of the conventional Stroop specifically activated the anterior cingulate, insula, promotor and inferior frontal regions. These activated regions in the current experiment are consistent with those activated in fMRI experiments that use a more traditional block design. Finally, analysis of the time course of fMRI signal changes demonstrated differential onset and offset of signal changes in these activated regions. The time course results suggest that the action of various brain areas can be temporally dissociated.