Experiment-Assisted Secondary Structure Prediction with RNAstructure
Experiment-Assisted Secondary Structure Prediction with RNAstructure
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DOI:
10.1007/978-1-4939-6433-8_10
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发表时间:
2016-01-01
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影响因子:
--
通讯作者:
Mathews, David H.
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文献类型:
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作者:
Xu, Zhenjiang Zech;Mathews, David H.
Experimental probing data can be used to improve the accuracy of RNA secondary structure prediction. The software package RNAstructure can take advantage of enzymatic cleavage data, FMN cleavage data, traditional chemical modification reactivity data, and SHAPE reactivity data for secondary structure modeling. This chapter provides protocols for using experimental probing data with RNAstructure to restrain or constrain RNA secondary structure prediction.