Atrial Fibrillation and Heart Failure: Epidemiology, Pathophysiology, Prognosis, and Management.

Atrial Fibrillation and Heart Failure: Epidemiology, Pathophysiology, Prognosis, and Management.
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DOI:
10.1016/j.ccep.2020.11.004
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发表时间:
2021-03-01
影响因子:
--
通讯作者:
Kalman, Jonathan M
Kalman, Jonathan M
中科院分区:
其他
文献类型:
--
作者:
Ariyaratnam, Jonathan P;Lau, Dennis H;Kalman, Jonathan M

文献摘要

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心房颤动(AF)和心力衰竭(HF)具有相似的危险因素,经常共存,并相互加强,形成恶性循环。有证据表明,射血分数降低的心衰(HFrEF)和射血分数保留的心衰(HFpEF)都存在房颤,增加了全因死亡和卒中的风险,特别是在发生房颤的情况下。导管消融可能是控制房颤症状和改善生活质量的有效策略。由于其具有挑战性的诊断,在很大程度上缺乏指导治疗的强有力的数据。改善与这些共存条件相关的结果需要进一步仔细调查。
Atrial fibrillation (AF) and heart failure (HF) have similar risk factors, frequently coexist, and potentiate each other in a vicious cycle. Evidence suggests the presence of AF in both HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF) increases the risk of all-cause mortality and stroke, particularly when AF is incident. Catheter ablation may be an effective strategy in controlling symptoms and improving quality of life in AF-HFrEF. Strong data guiding management of AF-HFpEF are lacking largely due to its challenging diagnosis. Improving outcomes associated with these coexistent conditions requires further careful investigation.