In vivo anthelmintic activity of Dryopteris crassirhizoma, Kochia scoparia, and Polygala tenuifolia against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus)
In vivo anthelmintic activity of Dryopteris crassirhizoma, Kochia scoparia, and Polygala tenuifolia against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus)
复制标题
粗鳞毛蕨、地肤子和细叶远志对金鱼 (Carassius auratus) 中指环虫 (Monogenea) 的体内驱虫活性
DOI：
10.1007/s00436-011-2592-0
复制
发表时间：
2012-03-01
影响因子：
2
通讯作者：
Wang, Gao-Xue
中科院分区：
文献类型：
--
作者：
Lu, Cheng;Zhang, Hong-Yu;Wang, Gao-Xue
In order to find natural agents againstDactylogyrus intermediusin goldfish, petroleum ether, chloroform, ethyl acetate, acetone, and methanol extracts of three medicinal plants (Dryopteris crassirhizoma,Kochia scoparia, andPolygala tenuifolia) were screened for antiparasitic properties using in vivo anthelmintic efficacy assay. Among these extracts investigated, methanolic extract ofD. crassirhizomawas observed the most effective with EC50value of 22.97 mg L−1after 48 h of exposure, which exhibited a 100% efficacy againstD. intermediusat 60.00 mg L−1, followed by the methanolic extracts ofK. scopariaandP. tenuifoliawith EC50values of 31.28 and 154.79 mg L−1, showing 100% efficacy againstD.intermediusat 60.00 and 500.00 mg L−1, respectively. In addition, acute toxicity assay indicated that 48-h LC50values of methanolic extracts ofD. crassirhizoma,K. scoparia, andP. tenuifoliawere 4.10-, 2.27-, and 5.00-fold higher than the corresponding EC50. The obtained results demonstrated that methanolic extracts ofD. crassirhizoma,K. scoparia, andP. tenuifoliahave the potential for the development of novel therapy for the control ofD. intermediusin aquaculture.
