Comparison of cochlear delay estimates using otoacoustic emissions and auditory brainstem responses

Comparison of cochlear delay estimates using otoacoustic emissions and auditory brainstem responses
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DOI:
10.1121/1.3168508
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发表时间:
2009-09-01
影响因子:
2.4
通讯作者:
Dau, Torsten
Dau, Torsten
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Harte, James M.;Pigasse, Gilles;Dau, Torsten

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已经进行了不同的尝试来直接测量动物中的频率特异性基底膜(BM)延迟,例如,BM振动的激光测速和听觉神经纤维记录。本研究使用耳声发射(OAE)和听觉脑干反应(ABR)来估计BM延迟非侵入性听力正常的人。从0.5到8 kHz的九个频率的短纯音作为刺激,小心量化由于使用具有不同上升时间的短纯音而可能产生的偏差。通过减去神经和突触延迟,从ABR潜伏期估计来估计BM延迟。这允许在同一受试者的大频率范围内比较个体OAE和BM延迟,并支持OAE从音调位置反射并通过反向行波带回耳蜗基底的理论。(c)2009年,美国声学学会。[DOI 10.1121/1.3168508]
Different attempts have been made to directly measure frequency specific basilar membrane (BM) delays in animals, e.g., laser velocimetry of BM vibrations and auditory nerve fiber recordings. The present study uses otoacoustic emissions (OAEs) and auditory brainstem responses (ABRs) to estimate BM delay non-invasively in normal-hearing humans. Tone bursts at nine frequencies from 0.5 to 8 kHz served as stimuli, with care taken to quantify possible bias due to the use of tone bursts with different rise times. BM delays are estimated from the ABR latency estimates by subtracting the neural and synaptic delays. This allows a comparison between individual OAE and BM delays over a large frequency range in the same subjects, and offers support to the theory that OAEs are reflected from a tonotopic place and carried back to the cochlear base via a reverse traveling wave. (c) 2009 Acoustical Society of America. [DOI: 10.1121/1.3168508]