Liver volumetry plug and play: do it yourself with ImageJ.

Liver volumetry plug and play: do it yourself with ImageJ.
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肝脏容量测定即插即用:使用 ImageJ 自行操作。

DOI:
10.1007/s00268-007-9197-x
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发表时间:
2007-11
影响因子:
2.6
通讯作者:
Dejong, Cornelis H. C.
Dejong, Cornelis H. C.
中科院分区:
医学3区
文献类型:
--
作者:
Dello, Simon A. W. G.;van Dam, Ronald M.;Slangen, Jules J. G.;de Poll, Marcel C. G. van;Bemelmans, Marc H. A.;Greve, Jan Willem W. M.;Beets-Tan, Regina G. H.;Wigmore, Stephen J.;Dejong, Cornelis H. C.

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残余肝体积小是术后肝功能衰竭的一个重要危险因素,可以通过使用放射图像分析软件的计算机断层扫描(CT)体积测定法准确预测。不幸的是,该软件价格昂贵,通常需要放射科医生的支持。ImageJ是由美国国立卫生研究院(NIH)开发的可免费下载的图像分析软件包,可将肝脏体积测定带到外科医生的桌面上。我们的目的是评估ImageJ用于肝脏CT容积测量的准确性。 ImageJ从http://www.rsb.info.nih.gov/ij/下载。回顾性分析15例结直肠癌肝转移患者行肝切除术的术前CT扫描资料。在ImageJ中打开扫描;在每个切片上手动勾画肝脏、所有转移灶和预期的实质横切线。将每个选定区域、转移灶、切除标本和残肝的面积乘以切片厚度以计算体积。将使用ImageJ测量的虚拟肝切除标本的重量与切除后病理检查期间获得的标本重量和计算体积进行比较。 使用ImageJ计算的体积与切除标本的实际测量重量之间存在良好的相关性(r² = 0.98,p < 0.0001)。重量/体积比为0.88 ± 0.04(标准误差),与我们早期使用CT-放射学软件的结果一致。 ImageJ可用于在个人计算机上进行精确的肝脏CT容积测定。该应用程序将CT容积测量带到外科医生的桌面上,无需花费任何费用,并且对于三级转诊患者特别有用,这些患者已经从转诊机构获得了适当的CD-ROM CT扫描。最有可能的体积和重量之间的差异是由于切除后的肝脏放血。
A small remnant liver volume is an important risk factor for posthepatectomy liver failure and can be predicted accurately by computed tomography (CT) volumetry using radiologic image analysis software. Unfortunately, this software is expensive and usually requires support by a radiologist. ImageJ is a freely downloadable image analysis software package developed by the National Institute of Health (NIH) and brings liver volumetry to the surgeon’s desktop. We aimed to assess the accuracy of ImageJ for hepatic CT volumetry. ImageJ was downloaded from http://www.rsb.info.nih.gov/ij/. Preoperative CT scans of 15 patients who underwent liver resection for colorectal cancer liver metastases were retrospectively analyzed. Scans were opened in ImageJ; and the liver, all metastases, and the intended parenchymal transection line were manually outlined on each slice. The area of each selected region, metastasis, resection specimen, and remnant liver was multiplied by the slice thickness to calculate volume. Volumes of virtual liver resection specimens measured with ImageJ were compared with specimen weights and calculated volumes obtained during pathology examination after resection. There was an excellent correlation between the volumes calculated with ImageJ and the actual measured weights of the resection specimens (r² = 0.98, p < 0.0001). The weight/volume ratio amounted to 0.88 ± 0.04 (standard error) and was in agreement with our earlier findings using CT-linked radiologic software. ImageJ can be used for accurate hepatic CT volumetry on a personal computer. This application brings CT volumetry to the surgeon’s desktop at no expense and is particularly useful in cases of tertiary referred patients, who already have a proper CT scan on CD-ROM from the referring institution. Most likely the discrepancy between volume and weight results from exsanguination of the liver after resection.
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