A resistant case of pemphigus gestationis successfully treated with cyclosporine
A resistant case of pemphigus gestationis successfully treated with cyclosporine
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DOI：
10.1556/1646.8.2016.1.3
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发表时间：
2016-03-01
影响因子：
--
通讯作者：
Ilgin, Bunyamin Ugur
中科院分区：
文献类型：
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作者：
Ozdemir, Ozhan;Atalay, Cemal Resat;Ilgin, Bunyamin Ugur
妊娠类天疱疮（PG）是一种罕见的妊娠期自身免疫性水疱性疾病，由抗基底膜区自身抗体引起。常见的临床表现是妊娠中期和晚期或产后不久出现的多发性瘙痒性荨麻疹丘疹和斑块、目标病变、水疱和水疱。该疾病通常用外用皮质类固醇和口服抗组胺药治疗。在更严重的情况下，需要全身使用皮质类固醇。在此，我们报告一例对环孢素治疗有反应的耐药 PG 病例。
Pemphigoid gestationis (PG) is a rare autoimmune blistering disease of pregnancy caused by antibasement membrane zone auto-antibodies. The usual clinical findings are multiple pruritic urticarial papules and plaques, target lesions, vesicles, and blisters that occur during the second and third trimesters of pregnancy or in the immediate postpartum period. The disease is often treated with topical corticosteroids and oral antihistaminics. In more severe cases, systemic corticosteroids are needed. Herein, we report a case of resistant PG that responded to treatment with cyclosporine.