Peripheral blood leukocyte populations in the elderly with and without periodontal disease.
Peripheral blood leukocyte populations in the elderly with and without periodontal disease.
复制标题
患有和不患有牙周病的老年人的外周血白细胞群。
DOI：
10.1111/j.1600-051x.1996.tb00622.x
复制
发表时间：
1996
影响因子：
6.7
通讯作者：
Magnusson,NI
中科院分区：
文献类型：
--
作者：
McArthur,WP;Bloom,K;Taylor,M;Wheeler,T;Smith,J;Magnusson,NI
老年人的牙周病还没有得到表征。初步报告表明，这种疾病是常见和严重的。据报道，老年人也会出现免疫应答缺陷。因此，假设免疫应答中与衰老相关的变化可能导致老年人牙周病的严重程度和发生。为了检验这一假设，测试了老年（65-75岁）受试者外周血中白细胞和白细胞亚群的百分比和数量，并用作这些个体免疫潜力的指标。确定了年龄和性别对几个测试参数的影响。除严重牙周病的老年组白细胞数量增加外，未发现其他白细胞参数的变化。提示老年人牙周病与外周血白细胞及白细胞亚群的增龄性变化无关。
Periodontal disease in the elderly has not been characterized. Initial reports suggest that the disease is common and severe. Deficiencies in the immune response have also been reported to occur in the elderly. Consequently it was hypothesized that aging‐related changes in the immune response may contribute to the severity and occurrence of periodontal disease in the elderly. To test that hypothesis, the % and number of leukocytes and leukocyte subsets in the peripheral blood of elderly (65–75 years) subjects were tested and used as indicators of the immune potential of those individuals. Age and gender effects on several of the parameters tested were identified. With the exception of increased number of leukocytes in the elderly group with severe periodontal disease, no other alteration in the leukocyte parameters tested were identified. These results suggest that periodontal disease in the elderly was not associated with obvious changes in the leukocyte and leukocyte subsets in the peripheral blood due to aging.