ETHNOPHARMACOLOGICAL INVESTIGATION OF GINGER (ZINGIBER-OFFICINALE)
ETHNOPHARMACOLOGICAL INVESTIGATION OF GINGER (ZINGIBER-OFFICINALE)
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DOI：
10.1016/0378-8741(89)90085-8
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发表时间：
1989-11-01
影响因子：
5.4
通讯作者：
CAPASSO, F
中科院分区：
文献类型：
--
作者：
MASCOLO, N;JAIN, R;CAPASSO, F
研究了一种药用植物白药根茎的乙醇提取物的抗炎、镇痛、解热、抗菌和降血糖活性。在大鼠中，提取物减少角叉菜胶引起的足肿胀和酵母引起的发热，但对抑制腹腔内乙酸引起的扭体无效。该提取物对家兔有降血糖作用。革兰氏阳性菌和革兰氏阴性菌的生长均受到明显抑制。使用大鼠腹膜白细胞观察到前列腺素释放效应的剂量依赖性抑制。
An ethanolic extract of the rhizomes of Zingiber officinale was investigated for anti-inflammatory, analgesic, antipyretic, antimicrobial and hypoglycaemic activities. In rats, the extract reduced carrageenan-induced paw swelling and yeast-induced fever but was ineffective in suppressing the writhing induced by intraperitoneal acetic acid. The extract produced blood glucose lowering in rabbits. The growth of both Gram-positive and Gram-negative bacteria was significantly inhibited. A dose-dependent inhibition of prostaglandin release effect was observed using rat peritoneal leucocytes.