Altered lung antioxidant status in patients with mild asthma
Altered lung antioxidant status in patients with mild asthma
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DOI：
10.1016/s0140-6736(99)01812-7
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发表时间：
1999-08-07
期刊：
影响因子：
168.9
通讯作者：
Sandström, T
中科院分区：
文献类型：
--
作者：
Kelly, FK;Mudway, J;Sandström, T
轻度哮喘患者的肺衬里液抗坏血酸（维生素C）和α-生育酚（维生素E）浓度较低，即使血液水平正常或升高。这些发现，沿着气道中氧化型谷胱甘肽含量的增加，表明哮喘患者的氧化应激增加。
Lung lining fluid ascorbic acid (vitamin C) and alpha-tocopherol (vitamin E) concentrations are low in patients with mild asthma even though blood levels are normal or increased. These findings, along with the presence of increased amounts of oxidised glutathione in their airways, indicate that patients with asthma are subject to increased oxidative stress.