Clinical impact of nocturnal ventricular tachyarrythmias in electrical storm
Clinical impact of nocturnal ventricular tachyarrythmias in electrical storm
复制标题
电风暴中夜间室性心律失常的临床影响
DOI：
10.1111/pace.14592
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Takayuki Inomata
中科院分区：
文献类型：
--
作者：
Naomasa Suzuki;Sou Otsuki;Daisuke Izumi;Rie Akagawa;Yuta Sakaguchi;Takahiro Hakamata;Yasuhiro Ikami;Yuki Hasegawa;Nobue Yagihara;Kenichi Iijima;Masaomi Chinushi;Takayuki Inomata
研究背景电风暴（electrical storm，ES）的发生率在白天明显较高.然而，ES期间夜间室性心动过速与预后之间的关系尚不清楚。因此，本研究的目的是调查的临床特征和结果的ES与午夜室性心动过速。MethodsWe包括48例连续患者谁有一个植入式心律转复除颤器或心脏除颤治疗除颤器之间植入2010年和2020年和那些谁经历了发作的院外ES发作。根据午夜（0：00 a.m.-6：00 a.m.）发生室性心律失常事件，包括室性心动过速（VT）和室颤（VF），我们将其分为两组（有午夜组：n= 27，无午夜组：n= 21）。比较两组患者的临床特征和结局。结果有午夜组患者多为男性，QRS时限较长，校正QT间期较无午夜组长（p<0.05）。全因死亡的发生率，特别是心力衰竭死亡，在午夜组中高于无午夜组（p< .01）。多变量分析显示ES期间午夜VT/VF的存在是心力衰竭死亡的唯一独立危险因素（HR = 18.9，95%CI = 1.98 - 181，p= 0.011）。在ES期间VT/VF分布的交感神经昼夜节律模式的丧失可能提示心脏疾病的晚期。
BackgroundThe incidence of electrical storm (ES) is significantly higher during the daytime. However, the association between nocturnal ventricular tachyarrythmias during ES and prognosis remains unclear. Therefore, this study aimed to investigate the clinical characteristics and outcomes of ES with midnight ventricular tachyarrythmias.MethodsWe included 48 consecutive patients who had an implantable cardioverter‐defibrillator or cardiac resynchronization therapy defibrillator implanted between 2010 and 2020 and those who had experienced the onset of an out‐of‐hospital ES episode. According to the midnight (0:00 a.m.–6:00 a.m.) occurrence of ventricular arrythmia events consisting of ventricular tachycardia (VT) and ventricular fibrillation (VF), we divided them into two groups (with‐midnight group:n= 27, without‐midnight group:n= 21). The clinical characteristics and outcomes of the two groups were compared.ResultsThe patients in the with‐midnight group were mostly males, had longer QRS duration, and longer corrected QT‐interval than those in the without‐midnight group (p< .05). The incidence of all‐cause death, especially heart failure death, was higher in the with‐midnight group than in the without‐midnight group (p< .01). Multivariate analysis showed that the presence of midnight VT/VF during ES was the only independent risk factors for heart failure death (HR = 18.9, 95%CI = 1.98−181,p= .011).ConclusionsThe presence of midnight VT/VF during ES might be associated with the poor prognosis. The loss of a sympathetic circadian pattern of VT/VF distribution during ES might suggest advanced stages of the cardiac disease.
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在植入式除颤器治疗时代，电风暴是不良长期结果的独立预测因素。
影响因子：
6.1
作者：
K. Gatzoulis;G. Andrikopoulos;T. Apostolopoulos;E. Sotiropoulos;G. Zervopoulos;J. Antoniou;S. Brili;C. Stefanadis
通讯作者：
C. Stefanadis
影响因子：
9.7
作者：
Conraads, Viviane M.;Spruit, Martijn A.;van Veldhuisen, Dirk J.
通讯作者：
van Veldhuisen, Dirk J.
影响因子：
2.8
作者：
Walsh, JT;Charlesworth, A;Cowley, AJ
通讯作者：
Cowley, AJ
影响因子：
39.3
作者：
Brigadeau, F;Kouakam, C;Kacet, S
通讯作者：
Kacet, S
影响因子：
3.5
作者：
Behnes, Michael;Mueller, Julian;Akin, Ibrahim
通讯作者：
Akin, Ibrahim