'Senile' osteoporosis reconsidered.

'Senile' osteoporosis reconsidered.
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重新考虑“老年”骨质疏松症。

DOI:
10.1001/jama.1989.03420070075034
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发表时间:
1989
期刊:
JAMA
影响因子:
--
通讯作者:
S. Greenspan
S. Greenspan
中科院分区:
--
文献类型:
--
作者:
N. Resnick;S. Greenspan

文献摘要

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相似文献

骨质疏松症是一种毁灭性的、病态的、昂贵的疾病,70岁以上的女性对骨质疏松症的影响最为深刻。尽管围绝经期妇女和老年妇女在骨矿物质代谢、骨质流失率、剩余骨的结构完整性、骨折的危险因素和持续骨折的类型等方面存在显著差异,但大多数关于其预防和治疗的研究都集中在围绝经期妇女身上。目前推荐的治疗方法是减缓围绝经期妇女的骨质流失,但对于骨质流失已经减缓或停止,且剩余骨骼数量和质量不足以预防骨折的老年妇女来说,效果可能较小。因此,应用目前可用的模式不太可能显著减轻这一人群骨质疏松症的后果。在此基础上,提出了今后的研究方向。
Osteoporosis is a devastating, morbid, and costly condition whose ravages are felt most profoundly by women over age 70 years. Yet most research on its prevention and treatment has focused on perimenopausal women, although there are significant differences between perimenopausal and older women in factors related to bone mineral metabolism, rates of bone loss, the structural integrity of remaining bone, risk factors for fractures, and the types of fractures sustained. Currently recommended therapies, which slow bone loss in perimenopausal women, may be of less benefit for older women whose loss of bone has already slowed or ceased and whose remaining bone may be of inadequate quantity and quality to prevent fracture. Thus, the application of currently available modalities is unlikely to mitigate significantly the consequences of osteoporosis in this population. Further research is urgently needed, and some directions for future investigation are suggested.
跌倒后受伤的危险因素。
DOI: --
发表时间: 1985
影响因子: 3.3
作者:
Melton3rd,LJ;Riggs,BL
通讯作者: Riggs,BL
更年期雌激素治疗和髋部骨折。
DOI: 10.7326/0003-4819-95-1-28
发表时间: 1981
影响因子: 39.2
作者:
Paganini-Hill,A;Ross,RK;Gerkins,VR;Henderson,BE;Arthur,M;Mack,TM
通讯作者: Mack,TM
DOI: 10.1172/jci111373
发表时间: 1984
期刊: The Journal of clinical investigation
影响因子: --
作者:
Tsai,KS;Heath3rd,H;Kumar,R;Riggs,BL
通讯作者: Riggs,BL
绝经后多个骨骼部位的骨质流失:与雌激素使用的关系。
DOI: 10.1016/0021-9681(83)90070-x
发表时间: 1983
期刊: Journal of chronic diseases
影响因子: --
作者:
Wasnich,R;Yano,K;Vogel,J
通讯作者: Vogel,J
DOI: 10.7326/0003-4819-102-3-319
发表时间: 1985-01-01
影响因子: 39.2
作者:
ETTINGER, B;GENANT, HK;CANN, CE
通讯作者: CANN, CE