Genetic heterogeneity of pestiviruses of ruminants in Switzerland
Genetic heterogeneity of pestiviruses of ruminants in Switzerland
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DOI：
10.1016/j.prevetmed.2005.01.020
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发表时间：
2005-11-15
影响因子：
2.6
通讯作者：
Peterhans, E
中科院分区：
文献类型：
--
作者：
Stalder, HP;Meier, P;Peterhans, E
我们对反刍动物鼠疫病毒进行了基因分析。从瑞士牛中分离的bbb150牛病毒性腹泻（BVD）病毒均为1基因型，其中e、h、k和b亚基因群的出现频率呈下降趋势。迄今为止，仅在瑞士检测到k亚基因群的代表。尽管绵羊中存在边界病的血清学证据，但仅分离出少数边界病病毒，它们都属于新类群3。血清学证据表明，瑞士的野生反刍动物也可能感染鼠疫病毒，但没有分离物可供分析。此外，我们描述了两种鼠疫病毒，一种是细胞培养污染物，另一种是从水牛中分离出来的，它们与最近提出的一种新型鼠疫病毒聚集在一起。(c) 2005 Elsevier B.V.版权所有
We have genetically analyzed ruminant pestiviruses. All > 150 bovine viral diarrhea (BVD) viruses isolated from cattle in Switzerland belonged to genotype 1, with subgenogroups e, h, k and b found in decreasing frequency. To date, representatives of subgenogroup k have been detected in Switzerland only. Despite serological evidence of Border disease in sheep, only few Border disease viruses have been isolated, all of which belong to the novel group 3. Serological evidence suggested that pestivirus infections may occur also in wild ruminants in Switzerland but no isolates are available for analysis. In addition, we describe two pestiviruses, one a cell culture contaminant and the other isolated from a buffalo, that cluster with a recently proposed novel pestivirus species. (c) 2005 Elsevier B.V. All rights reserved.