Xylose-DNA: Sequence-Dependent Duplex Stability as Function of Backbone Configuration
Xylose-DNA: Sequence-Dependent Duplex Stability as Function of Backbone Configuration
复制标题
木糖-DNA：序列依赖性双链体稳定性作为主链构型的函数
DOI：
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发表时间：
1995
期刊：
影响因子：
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通讯作者：
F. Seela
中科院分区：
文献类型：
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作者：
H. Rosemeyer;F. Seela
摘要 合成了由 2'-脱氧-β]-D-木糖腺苷和/或-胸苷构建的一系列同源寡聚或端粒寡核苷酸的碱基配对，并研究了其双链体形成的热力学。寡聚体（2'-脱氧木核苷酸）含有的 d(xA-xT) 元素越多，则比相应的常规寡聚体更稳定。
Abstract The base pairing of a series of homooligomeric or telomeric oligonucleotides built-up from 2′-deoxy-β]-D-xyloadenosine and/or -thymidine were synthesized and studied with respect to their thermodynamics of duplex formation. Oligo (2′-deoxyxylonucleotides) are more stable than the corresponding regular oligomers the more d(xA-xT) elements they contain.