SEROLOGICAL DIAGNOSIS OF DENGUE BY AN ELISA INHIBITION METHOD (EIM)
SEROLOGICAL DIAGNOSIS OF DENGUE BY AN ELISA INHIBITION METHOD (EIM)
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DOI：
10.1590/s0074-02761990000300012
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发表时间：
1990-07-01
影响因子：
2.8
通讯作者：
VAZQUEZ, S
中科院分区：
文献类型：
--
作者：
FERNANDEZ, RJ;VAZQUEZ, S
本文提出了一种用于登革热血清学诊断的ELISA抑制法（EIM），并与血凝抑制法（HI）和IgM捕获ELISA法（MAC-ELISA）进行了比较。根据灵敏度、特异性、性能和实用性讨论了这两种方法的优缺点。最后，我们建议补充纳入EIM和MAC-ELISA，以取代从事登革热诊断和监测的实验室的HI。
An ELISA Inhibition Method (EIM) was proposed for the serologic diagnosis of dengue, comparing its results with the Hemagglutination Inhibition (HI) and the IgM capture-ELISA (MAC-ELISA). Advantages and disadvantages of both methods are discussed according to sensitivity, specificity, performance and usefulness. As a conclusion we recommended the complementary inclusion of the EIM and MAC-ELISA substituting the HI for laboratories engaged in the diagnosis and surveillance of dengue.