The Short Physical Performance Battery is a discriminative tool for identifying patients with COPD at risk of disability.
The Short Physical Performance Battery is a discriminative tool for identifying patients with COPD at risk of disability.
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DOI：
10.2147/copd.s94377
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发表时间：
2015
影响因子：
2.8
通讯作者：
Sánchez-Nieto JM
中科院分区：
文献类型：
--
作者：
Bernabeu-Mora R;Medina-Mirapeix F;Llamazares-Herrán E;García-Guillamón G;Giménez-Giménez LM;Sánchez-Nieto JM
活动受限是发展慢性阻塞性肺疾病（COPD）相关残疾的风险因素。目前尚不清楚短体力活动成套测验（SPPB）用于识别COPD患者活动受限的有效性。确定SPPB总分及其三个组成部分（站立平衡、4米步态速度和五次重复坐立）用于识别COPD患者活动受限的临床有效性。这项横断面研究包括137名COPD患者，从西班牙的一家医院招募。测量肌肉力量测试和SPPB;然后，对患者进行自我报告的活动受限调查。SPPB评分的有效性进行了分析，通过开发受试者工作特征曲线，以分析识别活动受限患者的敏感性和特异性;通过检查不同类别的活动SPPB评分的组间差异;并通过将SPPB评分与力量测试相关联。只有SPPB总分和五次重复的坐立成分表现出良好的辨别能力;两者均显示受试者工作特征曲线下的面积大于0.7。在9种不同的活动中，有限制的患者的SPPB评分显著低于无限制的患者。SPPB评分与股四头肌测试中度相关（r>0.40），与握力测试相关性较低（r<0.30），增强了聚合效度和发散效度。SPPB综合评分截止值为10提供了识别活动受限的最佳准确性。本研究为SPPB总分和五次重复坐立试验评估COPD患者活动度的有效性提供了证据。这些测试也显示出作为筛选测试的潜力，用于识别具有移动限制的COPD患者。
Limited mobility is a risk factor for developing chronic obstructive pulmonary disease (COPD)-related disabilities. Little is known about the validity of the Short Physical Performance Battery (SPPB) for identifying mobility limitations in patients with COPD. To determine the clinical validity of the SPPB summary score and its three components (standing balance, 4-meter gait speed, and five-repetition sit-to-stand) for identifying mobility limitations in patients with COPD. This cross-sectional study included 137 patients with COPD, recruited from a hospital in Spain. Muscle strength tests and SPPB were measured; then, patients were surveyed for self-reported mobility limitations. The validity of SPPB scores was analyzed by developing receiver operating characteristic curves to analyze the sensitivity and specificity for identifying patients with mobility limitations; by examining group differences in SPPB scores across categories of mobility activities; and by correlating SPPB scores to strength tests. Only the SPPB summary score and the five-repetition sit-to-stand components showed good discriminative capabilities; both showed areas under the receiver operating characteristic curves greater than 0.7. Patients with limitations had significantly lower SPPB scores than patients without limitations in nine different mobility activities. SPPB scores were moderately correlated with the quadriceps test (r>0.40), and less correlated with the handgrip test (r<0.30), which reinforced convergent and divergent validities. A SPPB summary score cutoff of 10 provided the best accuracy for identifying mobility limitations. This study provided evidence for the validity of the SPPB summary score and the five-repetition sit-to-stand test for assessing mobility in patients with COPD. These tests also showed potential as a screening test for identifying patients with COPD that have mobility limitations.