Comparison of Pulmonary Function in Immigrant vs US-Born Asian Indians
Comparison of Pulmonary Function in Immigrant vs US-Born Asian Indians
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DOI：
10.1378/chest.09-1911
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发表时间：
2010-06-01
期刊：
影响因子：
9.6
通讯作者：
Quanjer, Philip H.
中科院分区：
文献类型：
--
作者：
Fulambarker, Ashok;Copur, Ahmet Sinan;Quanjer, Philip H.
目的：本研究调查健康成年美国出生的亚裔印度人和移民亚裔印度人的肺功能是否因出生国家、环境和社会经济因素而存在差异。设计：对居住在芝加哥大都市区的印度出生和美国出生的受试者进行 FEV1、FVC 和肺活量 25% 至 75% 之间的用力呼气中段流量 (FEF25-75) 的测量。采用 Hollingshead 社会地位指数来评估社会经济因素。 结果：有 262 名出生于印度（61.8% 男性）和 200 名出生于美国（50% 男性）的受试者是健康的终身不吸烟者；他们的年龄范围为 16 至 36 岁。与移民的亚裔印度男性和女性相比，美国出生的亚裔印度男性和女性身高更高，肺功能值（身高和年龄）也更高。女性中的差异最为明显：FVC 约为 7%，FEV1 约为 9%，FEF25-75 约为 17%。移民和美国出生的受试者在社会经济地位上没有差异。结论：我们得出的结论是，与移民亚裔印度男性和女性相比，美国出生的亚裔印度男性和女性在年龄和身高方面具有更高的肺功能值。这可能反映了不同环境条件的影响，从而导致出生年份肺容量的趋势。胸部 2010； 137(6):1398-1404
Objective: This study investigated whether there is a difference in pulmonary function between healthy adult US-born Asian Indians and immigrant Asian Indians attributable to country of birth, environmental, and socioeconomic factors.Design: FEV1, FVC, and forced mid-expiratory flow between 25% and 75% of vital capacity (FEF25-75) were measured in India-born and US-born subjects residing in the Chicago metropolitan area. Hollingshead Index of Social Position was used to evaluate socioeconomic factors.Results: There were 262 India-born (61.8% male), and 200 US-born (50% male) subjects who were healthy lifelong nonsmokers; their age range was 16 to 36 years. US-born Asian Indian men and women were taller and had higher pulmonary function values for height and age compared with immigrant Asian Indian men and women. The differences were most pronounced in women: about 7% for FVC, 9% for FEV1, and 17% for FEF25-75. Immigrant and US-born subjects did not differ in socioeconomic position.Conclusion: We conclude that US-born Asian Indian men and women have higher pulmonary function values for age and height compared with immigrant Asian Indian men and women. This probably reflects the effect of differing environmental conditions, which cause year-of-birth trends in lung volumes. CHEST 2010; 137(6):1398-1404