Diagnosis of palmar hyperhidrosis via questionnaire without physical examination.
Diagnosis of palmar hyperhidrosis via questionnaire without physical examination.
复制标题
无需体检，通过问卷调查诊断手汗症。
DOI：
10.1007/s10286-009-0006-5
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Burk,Robert
中科院分区：
文献类型：
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作者：
Keller,StevenM;Bello,Riccardo;Vibert,Betsy;Swergold,Gary;Burk,Robert
目的为了确定自我管理仪器诊断过度出汗状况的可靠性，包括手掌多汗症（PH），我们设计了两个连续的调查问卷，并比较了正常志愿者和一组有记录的PH患者的体格检查和汗液测量的反应。通过调查问卷对PH的可靠诊断将使分子流行病学研究成为可能，而不需要体格检查或受试者自我鉴定为正常或受PH影响。每个人完成一个或两个问卷，并进行体检。在休息和精神/情绪压力下测量鱼际隆起和前额的汗液产生。汗液测量，体检和问卷scores. ResultsForty七名受试者参加了这项研究，其中29人进行了汗液测量之间的相关性进行了评估。参与者对自己是否受到影响的感知与检查者对PH的视觉和触觉观察一致（P< 0.0005）。PH患者的平均峰值出汗率为1.59 mg/cm 2/min，而正常人群为0.37 mg/cm 2/min（P= 0.001）。PH组和正常组受试者的平均问卷1和2评分分别为7.10和0.36（P= 0.0005），5.145和0.045（P= 0.0005）。最大出汗率与问卷评分相关（Pearson相关系数= 0.723）。PH的分子流行病学研究可以可靠地进行，而不需要直接的身体检查。
ObjectivesIn order to determine the reliability of a self-administered instrument to diagnose excessive sweating conditions, including palmar hyperhidrosis (PH), we designed two successive questionnaires and compared responses with physical examination and sweat measurement in normal volunteers and a cohort of patients with documented PH. The reliable diagnosis of PH via questionnaire would enable molecular epidemiological studies without the need for physical examination or direct sweat measurement.MethodsSubjects self identified as either normal or affected by PH. Each completed one or both questionnaires and underwent physical examination. Sweat production from the thenar eminence and forehead was measured at rest and following mental/emotional stress. Correlation among sweat measurement, physical examination, and questionnaire score was assessed.ResultsForty-seven subjects enrolled in the study, 29 of whom underwent sweat measurements. The participants’ perception of whether they were affected agreed with the examiner’s visual and tactile observation of PH in all cases (P< 0.0005). The mean peak sweat rate for those participants with PH was 1.59 mg/cm2/min, while that of the normal cohort was 0.37 mg/cm2/min (P= 0.001). The mean questionnaire #1 and #2 scores for those participants with PH and the normal cohort was 7.10 versus 0.36 (P= 0.0005) and 5.145 versus 0.045 (P= 0.0005), respectively. Peak sweat rate correlated with questionnaire score (Pearson correlation coefficient = 0.723).InterpretationPalmar hyperhidrosis can be accurately diagnosed via questionnaire. Molecular epidemiological studies of PH may be reliably conducted without the need for direct physical examination.