Human tandem repeat sequences in forensic DNA typing

Human tandem repeat sequences in forensic DNA typing
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DOI:
10.1016/j.legalmed.2005.02.002
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发表时间:
2005-07-01
期刊:
影响因子:
1.5
通讯作者:
Jeffreys, Alec J.
Jeffreys, Alec J.
中科院分区:
医学4区
文献类型:
--
作者:
Tamaki, Keiji;Jeffreys, Alec J.

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DNA指纹技术的首次发展和法医DNA分型的开始已经有20年了。从那时起,人类串联重复DNA序列一直是法医DNA分析的主要目标。这些重复序列分为微型卫星(VNTRs)和微型卫星(STRs)。在这篇简短的综述中,我们讨论了这种串联重复序列的历史和当前的法医应用。2005爱思唯尔爱尔兰有限公司版权所有。
It has been 20 years since the first development of DNA fingerprinting and the start of forensic DNA typing. Ever since, human tandem repeat DNA sequences have been the main targets for forensic DNA analysis. These repeat sequences are classified into minisatellites (or VNTRs) and microsatellites (or STRs). In this brief review, we discuss the historical and current forensic applications of such tandem repeats. (c) 2005 Elsevier Ireland Ltd. All rights reserved.