Synthetic biology in the UK - An outline of plans and progress.
Synthetic biology in the UK - An outline of plans and progress.
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DOI：
10.1016/j.synbio.2016.09.003
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发表时间：
2016-12
影响因子：
4.8
通讯作者：
Kitney RI
中科院分区：
文献类型：
--
作者：
Clarke LJ;Kitney RI
合成生物学能够为跨越国内和国际生物经济的关键挑战提供新的解决方案。认识到这一巨大潜力以及促进其翻译和商业化的相关需求，英国政府于2011年委托制作了国家合成生物学路线图，并随后为其实施提供了关键支持。已经进行了关键的基础设施投资，并在发展一个由从业人员和利益团体组成的有效联系的社区方面取得了重要进展。已经建立了一些合成生物学研究中心、DNA合成代工厂、一个博士培训中心和一个创新知识中心，创建了一个全国分布和综合的互补设施和专业知识网络。英国合成生物学领导委员会于2016年发布了英国合成生物学战略计划，增加了对翻译和商业化过程的关注。50多家初创企业、中小企业和更大的公司在英国积极从事合成生物学，外来投资也开始源源不断。这些举措共同为刺激创新、积极促进国际研究和发展伙伴关系以及帮助从合成生物学中获得有益的利益以响应地方和全球的需求和挑战提供了重要的基础。
Synthetic biology is capable of delivering new solutions to key challenges spanning the bioeconomy, both nationally and internationally. Recognising this significant potential and the associated need to facilitate its translation and commercialisation the UK government commissioned the production of a national Synthetic Biology Roadmap in 2011, and subsequently provided crucial support to assist its implementation. Critical infrastructural investments have been made, and important strides made towards the development of an effectively connected community of practitioners and interest groups. A number of Synthetic Biology Research Centres, DNA Synthesis Foundries, a Centre for Doctoral Training, and an Innovation Knowledge Centre have been established, creating a nationally distributed and integrated network of complementary facilities and expertise. The UK Synthetic Biology Leadership Council published a UK Synthetic Biology Strategic Plan in 2016, increasing focus on the processes of translation and commercialisation. Over 50 start-ups, SMEs and larger companies are actively engaged in synthetic biology in the UK, and inward investments are starting to flow. Together these initiatives provide an important foundation for stimulating innovation, actively contributing to international research and development partnerships, and helping deliver useful benefits from synthetic biology in response to local and global needs and challenges.