Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients.

Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients.
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灯盏花素注射液提高西药对心绞痛患者的治疗效果。

DOI:
10.1371/journal.pone.0129969
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发表时间:
2015
期刊:
影响因子:
3.7
通讯作者:
Liu E
Liu E
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Wang C;Li Y;Gao S;Cheng D;Zhao S;Liu E

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评价灯盏花素注射液联合西药治疗冠心病心绞痛的疗效及不良反应。检索科克伦对照试验中心、Medline、Science Citation Index、EMBASE、中国知网、万方数据库、重庆维普信息数据库和中国生物医学数据库,以确定评价西药与灯盏花素注射液联合西药治疗心绞痛患者疗效的随机临床试验(RCT)。使用RevMan 5.1.0软件对纳入的研究进行分析。文献检索得到460项研究,其中16项研究符合选择标准。结果表明:灯盏花素联合西药治疗对心绞痛症状的改善上级单纯西药治疗(OR =3.77,95% CI:2.76~5.15),对心电图的改善也优于单纯西药治疗(OR=2.77,95% CI:2.16~3.53)。目前的证据表明,灯盏花素联合西药治疗效果上级单用西药。
To evaluate the beneficial and adverse effects of breviscapine injection in combination with Western medicine on the treatment of patients with angina pectoris. The Cochrane Central Register of Controlled Trials, Medline, Science Citation Index, EMBASE, the China National Knowledge Infrastructure, the Wanfang Database, the Chongqing VIP Information Database and the China Biomedical Database were searched to identify randomized clinical trials (RCTs) that evaluated the effects of Western medicine compared to breviscapine injection plus Western medicine on angina pectoris patients. The included studies were analyzed using RevMan 5.1.0 software. The literature search yielded 460 studies, wherein 16 studies matched the selection criteria. The results showed that combined therapy using Breviscapine plus Western medicine was superior to Western medicine alone for improving angina pectoris symptoms (OR =3.77, 95% Cl: 2.76~5.15) and also resulted in increased electrocardiogram (ECG) improvement (OR=2.77, 95% Cl: 2.16~3.53). The current evidence suggests that Breviscapine plus Western medicine achieved a superior therapeutic effect compared to Western medicine alone.
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发表时间: 2010-12-01
期刊: ACTA DIABETOLOGICA
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作者:
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