Excitatory components of the mammalian locomotor CPG

Excitatory components of the mammalian locomotor CPG
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DOI:
10.1016/j.brainresrev.2007.07.002
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发表时间:
2008-01-01
影响因子:
--
通讯作者:
Endo, Toshiaki
Endo, Toshiaki
中科院分区:
其他
文献类型:
--
作者:
Kiehn, Ole;Quinlan, Katharina A.;Endo, Toshiaki

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哺乳动物的运动在很大程度上直接由称为中枢模式发生器(CPG)的内在脊髓网络控制。这些网络的整体功能由抑制性和兴奋性神经元之间的相互作用控制。在本综述中,我们将讨论最近的研究结果,兴奋性突触传递网络功能的作用,包括特定的兴奋性神经元群体在协调肌肉活动和产生节律活动的作用。(c)2007 Elsevier B.V.保留所有权利。
Locomotion in mammals is to a large degree controlled directly by intrinsic spinal networks, called central pattern generators (CPGs). The overall function of these networks is governed by interaction between inhibitory and excitatory neurons. In the present review, we will discuss recent findings addressing the role of excitatory synaptic transmission for network function including the role of specific excitatory neuronal populations in coordinating muscle activity and in generating rhythmic activity. (c) 2007 Elsevier B.V. All rights reserved.