The significance of birth weight difference in discordant twins: a level to standardize?

The significance of birth weight difference in discordant twins: a level to standardize?
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DOI:
10.1034/j.1600-0412.1998.770106.x
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发表时间:
1998-01
影响因子:
4.3
通讯作者:
H. Yalcin;C. Zorlu;A. Lembet;S. Özden;O. Gökmen
H. Yalcin;C. Zorlu;A. Lembet;S. Özden;O. Gökmen
中科院分区:
医学2区
文献类型:
--
作者:
H. Yalcin;C. Zorlu;A. Lembet;S. Özden;O. Gökmen

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目的探讨双胎妊娠不同程度出生体重不一致的意义。设计:以人群为基础的研究。方法回顾性分析1995年12月31日至1995年12月31日的384例孕20周以上双胎妊娠的临床资料。根据婴儿出生体重的百分比差异,双胞胎被分为六类。双胞胎出生体重的差异是由较大的双胞胎的出生体重(较大双胞胎的出生体重-较小双胞胎的出生体重)/较大双胞胎的出生体重乘以100计算得出的。不同类别之间的关系和随后的围产期和新生儿的结果进行了评估。结果在384对双胞胎中,13例为单胎死胎,14例为双胎死胎。在357例双胎妊娠中,137例(38.4%)的不一致性为30%(10.1%)。低APGAR评分(30%不一致)的频率高于30%出生体重不一致(41.7%),24例30%的病例发生新生儿死亡,而< 10%不一致的患者的相应数字为1.5%。结论我们认为,双胎妊娠中不协调生长的定义应根据孕周进行分类,因为在妊娠的不同阶段,不协调生长对胎儿或新生儿的危害程度可能不同。
OBJECTIVE To evaluate the significance of different degrees of birth weight discordance in twin pregnancies. DESIGN Population based study. METHODS Three hundred and eighty-four twin gestations over 20 weeks of gestation during a two-year period ending in 31.12.1995 were retrospectively analyzed. Twins were stratified into six categories according to the percent difference in infant birth weight. The difference in percents was calculated from the larger twin; (Birth weight of larger twin--Birth weight of smaller twin)/Birth weight of larger twin and multiplied with 100. The relationship between different categories and the subsequent perinatal and neonatal outcomes was assessed. RESULTS Among 384 pairs thirteen patients were identified to have single fetal demise and fourteen patients were documented to have dead fetuses of both twin pairs. Of 357 twin gestations studied 137 (38.4%) had discordance of 30% (10.1%). The frequency of low APGAR score ( 30% discordance was higher than that of 30% birth weight discordance (41.7%) and in 24 cases with 30% experienced neonatal mortality whereas the corresponding figure for patients with < 10% discordance was 1.5%. CONCLUSION We postulate that definition of discordant growth in twin gestations should be categorized with respect to gestational week since the level of discordance prejudicing fetal or neonatal jeopardy may vary in different stages of pregnancy.