Pharmacogenomics in Cardiovascular Diseases.
Pharmacogenomics in Cardiovascular Diseases.
复制标题
心血管疾病中的药物基因组学。
DOI：
10.1002/cpz1.189
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发表时间：
2021-07
期刊：
影响因子：
--
通讯作者：
McDonough CW
中科院分区：
文献类型：
--
作者：
McDonough CW
心血管药物基因组学是研究和鉴定与心血管药物反应变异性、心血管药物相关结果或心血管药物相关不良事件相关的基因组标记。本概述介绍了心血管药物基因组学的简介和历史背景，以及设计心血管药物基因组学研究的方案。还包括构建心血管药物基因组学表型、设计复制或验证策略、常见统计方法以及如何将结果与所研究的心血管药物或心血管疾病联系起来的重要考虑因素。基本方案 1：设计心血管药物基因组学研究
Cardiovascular pharmacogenomics is the study and identification of genomic markers that are associated with variability in cardiovascular drug response, cardiovascular drug related outcomes, or cardiovascular drug related adverse events. This overview presents an introduction and historical background to cardiovascular pharmacogenomics, and a protocol for designing a cardiovascular pharmacogenomics study. Important considerations are also included for constructing a cardiovascular pharmacogenomics phenotype, designing the replication or validation strategy, common statistical approaches, and how to put the results in context with the cardiovascular drug or cardiovascular disease under investigation. Basic Protocol 1: Designing a Cardiovascular Pharmacogenomics Study
影响因子：
3.7
作者：
McDonough CW;Gillis NK;Alsultan A;Chang SW;Kawaguchi-Suzuki M;Lang JE;Shahin MH;Buford TW;El Rouby NM;Sá AC;Langaee TY;Gums JG;Chapman AB;Cooper-DeHoff RM;Turner ST;Gong Y;Johnson JA
通讯作者：
Johnson JA