A critique of methods for temperature imaging in single cells

A critique of methods for temperature imaging in single cells
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DOI:
10.1038/nmeth.3073
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发表时间:
2014-09-01
期刊:
影响因子:
48
通讯作者:
Jullien, Ludovic
Jullien, Ludovic
中科院分区:
生物学1区
文献类型:
--
作者:
Baffou, Guillaume;Rigneault, Herve;Jullien, Ludovic

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我们认为,标准的热力学考虑和标度定律表明,单个细胞不能通过内源性产热大幅提高其温度。这一说法严重质疑了最近报道在单个活细胞中测量温度异质性的工作的解释。
We argue that standard thermodynamic considerations and scaling laws show that a single cell cannot substantially raise its temperature by endogenous thermogenesis. This statement seriously questions the interpretations of recent work reporting temperature heterogeneities measured in single living cells.