Indication, efficiency and complications of intrathecal pump supported baclofen treatment in spinal spasticity.

Indication, efficiency and complications of intrathecal pump supported baclofen treatment in spinal spasticity.
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鞘内泵支持巴氯芬治疗脊柱痉挛的适应症、有效性和并发症。

DOI:
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发表时间:
1992
期刊:
Acta neurologica
影响因子:
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通讯作者:
F. Gerstenbrand
F. Gerstenbrand
中科院分区:
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文献类型:
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作者:
L. Saltuari;M. Kronenberg;M. Marosi;M. Kofler;L. Russegger;C. Rifici;P. Bramanti;F. Gerstenbrand

文献摘要

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对19例因各种原因引起的严重脊神经痉挛,口服解痉剂无效的患者,鞘内注射巴氯芬试验丸。在11名患者中植入了DAD(药物管理装置)[SynchroMedR Model 8611 H,Medtronic Inc.,Minneapolis,USA]。在这11例患者中,导管脱位或扭转是最常见的并发症。鞘内长期应用巴氯芬对所有患者都有效,因为减少了痉挛、屈肌痉挛和痉挛引起的疼痛。在某些情况下,马达的性能有所改善。
In 19 patients, who suffered from severe spinal spasticity of different etiologies and did not respond sufficiently to oral antispastic therapy, intrathecal Baclofen test boli were administered. In 11 patients a DAD (Drug Administration Device) [SynchroMedR Model 8611 H, Medtronic Inc. Minneapolis, USA] was implanted. Catheter dislocation or torsion was the most common complication to be observed in these 11 patients. Long term intrathecal Baclofen application was effective in all patients, as reducing spasticity, flexor spasms and spasm induced pain. In some cases the motor performance ameliorated.