MICROALBUMINURIA IN SYSTEMIC-SCLEROSIS
MICROALBUMINURIA IN SYSTEMIC-SCLEROSIS
复制标题
DOI：
10.1136/ard.51.3.384
复制
发表时间：
1992-03-01
影响因子：
27.4
通讯作者：
CATTELL, WR
中科院分区：
文献类型：
--
作者：
DAWNAY, A;WILSON, AGM;CATTELL, WR
一项前瞻性研究旨在确定 28 名系统性硬化症患者的尿白蛋白排泄情况。 在最初的筛查中，一名患者出现蛋白尿，三名患者出现微量白蛋白尿。 一年后，这些异常现象持续存在，其中两名患者的血清肌酐显着升高。 此外，另外三名患者出现微量白蛋白尿。 在由 10 名原发性雷诺氏病患者组成的对照组中，没有人出现微量白蛋白尿。 第二个对照组由 16 名患有无关皮肤病的患者组成，其中一名患者有微量白蛋白尿，一名患者有蛋白尿，但这两名患者都有高血压病史。 结论是，微量白蛋白尿在系统性硬化症患者中比具有其他皮肤病但无血管疾病的同龄患者更常见。
A prospective study was performed to determine urinary albumin excretion in a group of 28 patients with systemic sclerosis. At the initial screen one patient had proteinuria and three had microalbuminuria. One year later these abnormalities persisted and in two of of the patients serum creatinine had significantly increased. In addition, a further three patients had developed microalbuminuria. In a control group of 10 patients with primary Raynaud's disease none had microalbuminuria. In a second control group of 16 patients with unrelated skin diseases one patient had microalbuminuria and one proteinuria, but both these patients had a history of hypertension. It is concluded that microalbuminuria is more common in patients with systemic sclerosis than in patients of equivalent age with other dermatological conditions but no vascular disease.