Comparative epidemiology of gastric cancer between Japan and China
Comparative epidemiology of gastric cancer between Japan and China
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DOI：
10.3748/wjg.v17.i39.4421
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发表时间：
2011-10-21
影响因子：
4.3
通讯作者：
Inoue, Manami
中科院分区：
文献类型：
--
作者：
Lin, Yingsong;Ueda, Junko;Inoue, Manami
目的：阐明日本和中国胃癌流行病学的相似性和差异。方法：对PubMed数据库进行全面的文献检索。还引用了中国发表的相关文献。2008年的发病率和死亡率数据来自国际癌症研究机构发布的Cancer Mondial数据库，网址为http://www-dep.iarc.fr/.RESULTS：胃癌仍然是日本和中国的重大公共卫生负担。幽门螺杆菌（H.幽门螺杆菌）在这两个国家的成年人群中的定植率都很高。在这两个国家的干预研究中积累的证据表明H。根除幽门螺杆菌可降低胃癌发病率。然而，在胃癌的许多方面，包括发病率和死亡率的模式，H。pylori感染、H. pylori菌株，胃癌的危险性大小与H.幽门螺杆菌感染，以及与饮食习惯的关系。与中国相比，日本的H.青少年幽门螺杆菌感染。虽然日本的队列研究主导了关于胃癌和饮食习惯之间关系的文献，但中国的许多病例对照研究表明，大量摄入腌制鱼类和蔬菜与胃癌风险之间存在正相关。需要一个多学科的研究方法来了解不同菌株之间的相互作用H。幽门螺杆菌、宿主因素及其他生活方式和环境因素在两国胃癌发生中的作用。幽门螺杆菌，以及在胃癌的许多方面的差异，提供了一个很好的机会，建立中日合作。(C)2011年百世登。All rights reserved.
AIM: To clarify the similarities and differences in gastric cancer epidemiology between Japan and China.METHODS: A comprehensive literature search of the PubMed database was performed. The relevant literature published in China was also been cited. Data on incidence and mortality rates in 2008 were obtained from the Cancer Mondial database, published by International Agency for Research on Cancer at http://www-dep.iarc.fr/.RESULTS: Gastric cancer remains a significant public health burden in both Japan and China. The prevalence of Helicobacter pylori (H. pylori) colonization is high in the adult populations of both countries. Accumulating evidence from intervention studies in both countries has shown the effectiveness of H. pylori eradication in reducing gastric cancer incidence. There are differences, however, in many aspects of gastric cancer, including patterns of incidence and mortality, trends in the prevalence of H. pylori infection, H. pylori strains, the magnitude of risk of gastric cancer related to H. pylori infection, and associations with dietary habits. Compared with China, Japan has seen a more rapid decline in H. pylori infection among adolescents. While Japanese cohort studies have dominated the literature concerning the associations between gastric cancer and dietary habits, numerous case-control studies in China suggest a positive association between a high intake of preserved fish and vegetables and gastric cancer risk. There is a need for a multidisciplinary research approach to understand the interactions between various strains of H. pylori, host factors, and other lifestyle and environmental factors in gastric carcinogenesis in both countries.CONCLUSION: The shared high incidence of gastric cancer and high prevalence of H. pylori, as well as differences in many aspects of gastric cancer, provide an excellent opportunity to establish Sino-Japanese collaborations. (C) 2011 Baishideng. All rights reserved.