JEZB special issue on animal gene regulatory network evolution

JEZB special issue on animal gene regulatory network evolution
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JEZB动物基因调控网络进化特刊

DOI:
10.1002/jez.b.23186
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发表时间:
2023
期刊:
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution
影响因子:
--
通讯作者:
Rebeiz, Mark
Rebeiz, Mark
中科院分区:
--
文献类型:
--
作者:
Williams, Thomas M.;Rebeiz, Mark

文献摘要

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保留字:动物;顺式调节元件;发展;进化;基因调控网络;后生动物;形态学;转录因子EN动物顺式调节元件发育进化基因调节网络后生动物形态转录因子内斯230301进化-发育领域中的一个形成性概念是基因调节网络(以下称为GRNs)在发育过程中基因表达模式化中的作用以及这些网络在形态进化中的作用。同源结构之间的差异可能是由相当大的差异之间的各自的翅膀和鞘翅GRN,或如何微妙的差异,在重点发展阶段揭示了主要的时间差异,在整个保守的GRN的基因表达。在“GRN概念作为进化发育生物学的指南”中,作者特别注意转录因子与其靶基因的I cis i-调节元件(克雷斯)之间的调节连接。[摘自文章]
Keywords: animals; cis-regulatory element; development; evolution; gene regulatory networks; metazoa; morphology; transcription factor EN animals cis-regulatory element development evolution gene regulatory networks metazoa morphology transcription factor 89 91 3 02/13/23 20230301 NES 230301 A formative concept in the evo-devo field has been the role of gene regulatory networks (hereafter GRNs) in patterning gene expression during development and the role that these networks play in the evolution of form. The differences between homologous structures might be explained by considerable differentiation among respective wing and elytra GRNs, or how subtle differences in the focal developmental stages reveal major temporal differences in gene expression across a conserved GRN. In" the GRN concept as a guide for evolutionary developmental biology", the authors draw particular attention to regulatory connections between transcription factors and I cis i-regulatory elements (CREs) of their target genes.[Extracted from the article]