Evidence for a temporal factor in the occupation of available synaptic sites during the development of the dentate gyrus.

Evidence for a temporal factor in the occupation of available synaptic sites during the development of the dentate gyrus.
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齿状回发育过程中可用突触位点占用的时间因素的证据。

DOI:
10.1016/0006-8993(72)90514-8
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发表时间:
1972
期刊:
影响因子:
2.9
通讯作者:
W. Cowan
W. Cowan
中科院分区:
医学3区
文献类型:
--
作者:
David I. Gottlieb;W. Cowan

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Fig. 1. A, Schematic representation of the commissural and ipsilateral association connections of the dentate gyrus (DG). Both pathways arise from cells in the adjoining hippocampal field CAa and terminate within the inner one-third of the dendritic field of the dentate granule ceils. The small arrows indicate the gradient in cell generation in the dentate gyrus, and the bold vertical line marks the midline of the brain. B, A camera lucida drawing of a Golgi preparation of a dentate granule cell to show the site of termination of the ipsilateral association and commissural pathways in the region marked by the large arrows. C, The distribution of silver grains in an autoradiograph of the dentate gyrus 48 h after the injection of [SH] leucine into field CAs of the hippocarnpus of one side, at a level slightly caudal to that depicted in A. The grains due to the ipsilateral and the commissurai pathways were counted in traverses at points A and B (Fig. 1A); lines'a'and'b'mark the outer limit of the layer of granule cell somata; the vertical line parallel to the ordinate indicates the background level of radioactivity in this experiment.