Distribution of the outer membrane haem receptor protein ChuA in environmental and human isolates of Escherichia coli
Distribution of the outer membrane haem receptor protein ChuA in environmental and human isolates of Escherichia coli
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DOI：
10.1078/1438-4221-00123
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发表时间：
2001-08-01
影响因子：
4.1
通讯作者：
Roggenkamp, A
中科院分区：
文献类型：
--
作者：
Hoffmann, H;Hornef, MW;Roggenkamp, A
ChuA是大肠杆菌的血红素受体，被认为与大肠杆菌的致病性有关。大肠杆菌菌株引起肠外感染。我们调查了大肠杆菌中chuA的感染率和分布。对304株不同来源的大肠杆菌进行了分析。30%的E.大肠埃希菌和70%左右的大肠埃希菌。从人源分离的大肠杆菌菌株携带chuA。从健康志愿者肠道中分离出的细菌和从肠外感染中分离出的细菌在chuA患病率上没有差异。我们的研究结果表明，ChuA可能参与人类宿主的定殖。
ChuA, the haem receptor of Escherichia coli, is thought to contribute to the pathogenicity of E. coli strains causing extraintestinal infections. We investigated the prevalence and distribution of chuA in E. coli analysing 304 strains from different origins. 30% of E. coli strains isolated from the environment and about 70% of E. coli strains isolated from human sources carried chuA. No difference in chuA prevalence was found between commensals isolated from the intestine of healthy volunteers and isolates from extraintestinal infections. Our results indicate that ChuA might be involved in the colonization of human hosts.