In Situ-Generated Niobium-Catalyzed Synthesis of 3-Pyrroline Derivatives via Ring-Closing Metathesis Reactions
In Situ-Generated Niobium-Catalyzed Synthesis of 3-Pyrroline Derivatives via Ring-Closing Metathesis Reactions
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DOI：
10.1021/acsomega.8b01642
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发表时间：
2018-08-01
期刊：
影响因子：
4.1
通讯作者：
Obora, Yasushi
中科院分区：
文献类型：
--
作者：
Fuji, Maito;Chiwata, Jintaro;Obora, Yasushi
以原位生成的活性铌配合物为催化剂，催化N，N-二烯丙基对甲苯磺酰胺的闭环复分解反应，合成了相应的3-吡咯啉衍生物。以NbCl_5、三甲基氯硅烷、Zn和PhCHCl_2为原料，在四氢呋喃中形成了铌配合物。Nb配合物对闭环复分解反应具有很高的催化活性。
An active in situ generated Nb complex was used as a catalyst in the ring-closing metathesis reaction of N,N-diallyl-p-toluenesulfonamide to afford the corresponding 3-pyrroline derivative. The Nb complex was formed from NbCl5, trimethylsilyl chloride, Zn and PhCHCl2 in retrahydrofuran. The Nb complex displayed high catalytic activity toward ring-closing metathesis reactions.