Can acute pain treatment reduce postsurgical comorbidity after breast cancer surgery? A literature review.
Can acute pain treatment reduce postsurgical comorbidity after breast cancer surgery? A literature review.
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DOI：
10.1155/2015/641508
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发表时间：
2015
影响因子：
--
通讯作者：
Sawa T
中科院分区：
文献类型：
--
作者：
Amaya F;Hosokawa T;Okamoto A;Matsuda M;Yamaguchi Y;Yamakita S;Taguchi T;Sawa T
局部镇痛，阿片类药物和几种口服镇痛药通常用于治疗乳腺癌手术后的急性疼痛。虽然所有这些治疗方法都可以抑制急性术后疼痛，但越来越多的证据表明，手术中使用的镇痛药类型不同，术后合并症也会有所不同。我们目前的研究回顾了用于急性疼痛治疗的镇痛药对乳腺癌手术后发生的主要合并症的影响。大量的临床研究探讨了急性镇痛方案与常见合并症的关系，包括术后恢复质量不佳、术后持续疼痛和癌症复发。以往的研究表明，镇痛方式的选择确实会影响术后的合并症。一般来说，局部镇痛药的使用对合并症的发生有有益的作用。为了确定乳腺癌手术后的最佳镇痛选择，未来需要进行基于对合并症状态明确定义的前瞻性研究。
Regional analgesia, opioids, and several oral analgesics are commonly used for the treatment of acute pain after breast cancer surgery. While all of these treatments can suppress the acute postsurgical pain, there is growing evidence that suggests that the postsurgical comorbidity will differ in accordance with the type of analgesic used during the surgery. Our current study reviewed the effect of analgesics used for acute pain treatments on the major comorbidities that occur after breast cancer surgery. A considerable number of clinical studies have been performed to investigate the relationship between the acute analgesic regimen and common comorbidities, including inadequate quality of recovery after the surgery, persistent postsurgical pain, and cancer recurrence. Previous studies have shown that the choice of the analgesic modality does affect the postsurgical comorbidity. In general, the use of regional analgesics has a beneficial effect on the occurrence of comorbidity. In order to determine the best analgesic choice after breast cancer surgery, prospective studies that are based on a clear definition of the comorbidity state will need to be undertaken in the future.