Moxibustion for treating menopausal hot flashes: a randomized clinical trial
Moxibustion for treating menopausal hot flashes: a randomized clinical trial
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DOI：
10.1097/gme.0b013e318198cdf7
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发表时间：
2009-07-01
影响因子：
2.7
通讯作者：
Choi, Sun-Mi
中科院分区：
文献类型：
--
作者：
Park, Ji-Eun;Lee, Myeong Soo;Choi, Sun-Mi
目的：潮热是一种常见的绝经后症状，约75%的更年期妇女经历。妇女经常求助于补充和替代药物来缓解潮热。莫西沙星就是这样一种药物。本研究的目的是评估艾灸对围绝经期和绝经后妇女潮热的影响。方法：将51名参与者随机分为三组，即灸1组、灸2组和等候组（对照组）。艾灸组在穴位进行14次艾灸治疗，疗程4周。我们的方案得到了来自临床专家（艾草1）或已发表文献（艾草2）的证据的支持，我们在研究结束后对所有参与者进行了额外的2周随访。我们的主要结局指标是潮热的频率和严重程度。次要结果参数包括生活质量（更年期特定生活质量量表）和更年期评定量表。到第4周，治疗组和对照组参与者之间潮热的严重程度和频率的差异具有统计学意义。此外，有一个统计学上的显着差异，治疗组2和其他groups.Conclusions之间的更年期特定的生活质量量表评分：我们的研究结果表明，艾灸减少的频率和严重程度的更年期潮热与对照组相比。我们建议进行更大样本的进一步研究，并可能包括安慰剂对照。
Objective: A hot flash is a general postmenopausal symptom experienced by approximately 75% of climacteric women. Women often turn to complementary and alternative medicines to relieve hot flashes. Moxibustion is one such medication. The aim of this study was to evaluate the effect of moxibustion on hot flashes in perimenopausal and postmenopausal women.Methods: Fifty-one participants were randomly assigned into three groups, namely, moxibustion 1, moxibustion 2, and waiting list (control). The moxibustion groups received 14 sessions of moxibustion treatment for 4 weeks at acupuncture points. Our protocol was supported by evidence from clinical experts (Moxa 1) or published literature (Moxa 2), and we followed all participants for an additional 2 weeks after the end of the study. Our primary outcome measures were frequency and severity of hot flashes. Secondary outcome parameters included quality of life (Menopausal-Specific Quality of Life Scale) and Menopause Rating Scale.Results: Fifty-one women participated in our study. By week 4, the difference in severity and frequency of hot flashes had become statistically significant between the treatment groups and the control participants. In addition, there was a statistically significant difference in Menopausal-Specific Quality of Life Scale scores between treatment group 2 and the other groups.Conclusions: Our results suggest that moxibustion reduces both the frequency and severity of menopausal hot flashes as compared with those in control participants. We would recommend further studies with larger samples and possibly including placebo controls.