Co-infusion of high-dose haploidentical donor cells and CD19-targeted CART cells achieves complete remission, successful donor engraftment and significant CART amplification in advanced ALL
Co-infusion of high-dose haploidentical donor cells and CD19-targeted CART cells achieves complete remission, successful donor engraftment and significant CART amplification in advanced ALL
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高剂量单倍体供体细胞和 CD19 靶向 CART 细胞的共输注可在晚期 ALL 中实现完全缓解、成功的供体植入和显着的 CART 扩增
DOI:
10.1177/1758835920927605
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发表时间:
2020-01
影响因子:
4.9
通讯作者:
Guo Mei
中科院分区:
文献类型:
--
作者:
Yu Changlin;Cai Bo;Wang Yao;Wu Zhiqiang;Hu Kaixun;Sun Qiyun;Qiao Jianhui;Fang Yanhong;Zuo Hongli;Wang Yi;Dong Zheng;Zhang Zechuan;Huang Yajing;Liu Zhiqing;Liu Tieqiang;Ai Huisheng;Han Weidong;Guo Mei
Autologous CD19-targeted chimeric antigen receptor-modified T cells (CD19-CART) remarkably improved the outcome of patients with advanced B-cell acute lymphoblastic leukemia (B-ALL). However, the application and outcomes of allogeneic CART cells is still
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DOI:
10.1038/nrclinonc.2017.148
发表时间:
2018-01
期刊:
Nature reviews. Clinical oncology
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2014-10-16
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2015-03
期刊:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
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