BEHAVIORAL-EVALUATION OF ALZHEIMER-DISEASE IN CLINICAL-TRIALS - DEVELOPMENT OF THE JAPANESE VERSION OF THE GBS SCALE
BEHAVIORAL-EVALUATION OF ALZHEIMER-DISEASE IN CLINICAL-TRIALS - DEVELOPMENT OF THE JAPANESE VERSION OF THE GBS SCALE
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DOI：
10.1097/00002093-199100051-00008
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发表时间：
1991-01-01
影响因子：
2.1
通讯作者：
HASEGAWA, K
中科院分区：
文献类型：
--
作者：
HOMMA, A;NIINA, R;HASEGAWA, K
GBS量表有4个分量表，共26个项目，是一种痴呆综合征的行为评定量表，目前在日本被用作评估痴呆症药物治疗效果的措施之一。本文对日本版 GBS 量表（GBSS-J）在 246 名痴呆症患者中的信度和效度进行了检验。两对评估者独立评估 20 名患者，以测试 26 个项目的评估者间可靠性。皮尔逊相关系数表明，除九个项目外，评分者之间的一致性良好。通过与功能评估分期进行比较来检验 26 个项目的有效性。身体残疾通过快速残疾评定量表进行评估。 GBSS-J的20个项目测量了痴呆的严重程度，具有足够的效度。此外，根据方差和协方差分析的结果，饮食项目、身体活动受损、觉醒受损和易怒与身体残疾的严重程度相关，而不是与痴呆相关。尽管除了痴呆症常见的不同症状的分量表外，三个分量表的 Cronbach's alpha 的内部信度都相对较高，但对 26 个项目的因子分析提出了关于原始四个分量表的构建效度的问题。
GBS scale with four subscales and 26 total items is a behavior rating scale for dementia syndromes, and is now being used as one of the measures to assess the effects of drug therapy in dementia in Japan. In this article, the reliability and validity of the Japanese version of GBS Scale (GBSS-J) in 246 patients with dementia are examined. Two pairs of raters independently rated 20 patients to test inter-rater reliability of the 26 items. Pearson's correlation coefficients indicated good agreement between the raters except for nine items. The validity of the 26 items was examined by comparing them with the Functional Assessment Staging. Physical disability was evaluated by the Rapid Disability Rating Scale. Twenty items of GBSS-J measured the severity of dementia with sufficient validity. In addition, the items of eating, impaired physical activity, impaired wakefulness, and irritability were related to severity of physical disability rather than to dementia by the results from an analysis of variance and covariance. Although internal reliabilities by Cronbach's alpha of the three subscales were relatively high except for the subscale of different symptoms common in dementia, a factor analysis of the 26 items raised questions concerning the construct validity of the original four subscales.