Low carbohydrate diets improve atherogenic dyslipidemia even in the absence of weight loss

Low carbohydrate diets improve atherogenic dyslipidemia even in the absence of weight loss
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DOI:
10.1186/1743-7075-3-24
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发表时间:
2006-06-21
影响因子:
4.5
通讯作者:
Volek, Jeff S.
Volek, Jeff S.
中科院分区:
医学3区
文献类型:
--
作者:
Feinman, Richard D.;Volek, Jeff S.

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由于其对胰岛素的影响,碳水化合物限制是减肥和糖尿病的明显饮食选择之一。这些干预措施通常会导致膳食脂肪水平高于官方建议,并且由于对心血管风险的潜在影响而长期受到批评,尽管许多文献报告表明,即使在没有减肥的情况下,它们实际上也具有保护作用。Krauss等人(AJCN,2006年)最近的一份报告将减肥和碳水化合物限制的影响分开。他们清楚地证实,在没有体重减轻或存在较高饱和脂肪的情况下,碳水化合物限制导致致动脉粥样硬化脂质状态的改善。不同的是,低脂饮食似乎需要减肥才能有效改善致动脉粥样硬化性血脂异常。
Because of its effect on insulin, carbohydrate restriction is one of the obvious dietary choices for weight reduction and diabetes. Such interventions generally lead to higher levels of dietary fat than official recommendations and have long been criticized because of potential effects on cardiovascular risk although many literature reports have shown that they are actually protective even in the absence of weight loss. A recent report of Krauss et al. (AJCN, 2006) separates the effects of weight loss and carbohydrate restriction. They clearly confirm that carbohydrate restriction leads to an improvement in atherogenic lipid states in the absence of weight loss or in the presence of higher saturated fat. In distinction, low fat diets seem to require weight loss for effective improvement in atherogenic dyslipidemia.