Neighborhood Socioeconomic Status and Cognitive Trajectories in a Diverse Longitudinal Cohort
Neighborhood Socioeconomic Status and Cognitive Trajectories in a Diverse Longitudinal Cohort
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DOI：
10.1080/07317115.2017.1282911
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发表时间：
2018-01-01
影响因子：
2.8
通讯作者：
Beckett, Laurel
中科院分区：
文献类型：
--
作者：
Meyer, Oanh L.;Mungas, Dan;Beckett, Laurel
目的：虽然个人层面的社会经济地位与不良结果相关，但关于社会背景如何影响认知结果的了解较少。我们研究了邻里社会经济地位（NSES）对基线认知功能和轨迹的下降。方法：样本（N=480）来自一个纵向队列招募研究认知功能。混合效应模型研究了NSES对基线和执行功能，语义记忆，情节memory.Results的变化率的影响：NSES是正相关的语义记忆分数在基线，但不与执行功能或情节记忆调整模型，也不与认知变化的纵向分析。在探索性分析中，对于患有痴呆症的个人，那些具有较高的NSES下降更快的执行功能和语义记忆比那些具有较低的NSES.Conclusions：结果表明，NSES具有有限的影响独立的个人特征，然而，研究结果显示了一个复杂的关系，NSES和下降，NSES的影响只观察到个人与痴呆症。结果进行了讨论的背景下，cognitive reserve.Clinical的影响：临床评估的个人谁提出与认知障碍可能会受益于从患者的邻里背景的理解。
Objectives: Although individual-level socioeconomic status is associated with poor outcomes, less is known regarding how the social context might affect cognitive outcomes. We examined the effect of neighborhood socioeconomic status (NSES) on baseline cognitive function and trajectories of decline.Methods: The sample (N=480) came from a longitudinal cohort recruited to study cognitive function. Mixed effects models examined the influence of NSES on baseline and rate of change in executive function, semantic memory, and episodic memory.Results: NSES was positively associated with semantic memory scores at baseline, but not with executive function or episodic memory in adjusted models, nor was it associated with cognitive change in longitudinal analyses. In exploratory analyses, for individuals with dementia, those with higher NSES declined faster in executive function and semantic memory than did those with lower NSES.Conclusions: Results suggest that NSES has limited effects independent of personal characteristics; however, findings showed a complex relation of NSES and decline, with NSES effects observed only for individuals with dementia. Results are discussed in the context of cognitive reserve.Clinical Implications: Clinical assessments of individuals who present with cognitive impairment might benefit from an understanding of the neighborhood context from which patients come.