An investigation into the sensitivity of shear wave ultrasound elastography to measure the anterior bladder wall pressure in patients with neurogenic bladder
An investigation into the sensitivity of shear wave ultrasound elastography to measure the anterior bladder wall pressure in patients with neurogenic bladder
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DOI：
10.4103/jfmpc.jfmpc_84_19
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发表时间：
2019-04
影响因子：
1.4
通讯作者：
Alireza Ghorbani Bavani;M. Hanafi;M. Sarkarian
中科院分区：
文献类型：
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作者：
Alireza Ghorbani Bavani;M. Hanafi;M. Sarkarian
前言和目的：由于逼尿肌的高顺应性，尿动力学检查被广泛用于评价膀胱功能。这种侵略性和不舒服的测试对儿童来说尤其困难。本研究旨在确定剪切波超声弹性成像（SWE）作为评价膀胱生物力学特性的一种新方法，用于测量神经源性膀胱（NB）儿童膀胱前壁压力的敏感性。材料与方法：本文对30例疑似NB患儿和20例健康儿童进行了前瞻性临床研究。这些儿童于2018年转诊至Ahwaz戈莱斯坦医院。临床评估后，对NB儿童进行尿动力学检查，并测量逼尿肌顺应性（cm/H2O）。对两组的膀胱前壁（估计膀胱容量（EBC）50%）进行SWE超声检查。剪切波速度（SWS）和逼尿肌顺应性之间的关系估计使用皮尔逊的相关系数。两组SWS比较采用独立t检验。结果如下：在NB患者中，膀胱前壁的平均SWS与逼尿肌顺应性之间存在显著相关性（R = 0.89，P = 0.0001）。正常组与NB组比较，NB组膀胱前壁平均SWS明显高于正常组（1.88 ± 0.88 m/s vs.0.94 ± 0.15; P = 0.0001）。SWS与患者性别、年龄、体重、体重指数无显著相关性（P > 0.05）。结论：结果表明，SWE可作为尿动力学检查的一种有用的替代方法，用于评价儿童NB（膀胱功能障碍）。
Introduction and Objective: Urodynamic testing (urodynamics) is widely used for evaluating bladder function as a result of high detrusor compliance. This aggressive and uncomfortable test is especially difficult for children. This study aimed to determine the sensitivity of shear wave ultrasound elastography (SWE) as a new method for evaluating the biomechanical characteristics of bladder to measure the anterior bladder wall pressure in children with neurogenic bladder (NB). Materials and Methods: The present prospective clinical study was carried out on 30 children with allegedly NB and 20 healthy children as control group. These children referred to Ahwaz Golestan Hospital in 2018. After clinical evaluations, urodynamics was performed for children with NB and detrusor compliance was measured in cm/H2O. The ultrasonography of the SWE was performed on the anterior wall of the bladder (Estimated bladder capacity (EBC) 50%) for the two groups. The relationship between shear wave speed (SWS) and detrusor compliance was estimated using Pearson's correlation coefficient. Independent t-test was used to compare SWS between two groups. Results: In patients with NB, there was a significant relationship between the mean SWS of the anterior bladder wall and detrusor compliance (R = 0.89, P = 0.0001). The comparison between normal and NB groups showed that the mean SWS of the anterior bladder wall in the patients was significantly higher than the healthy group (1.88 ± 0.88 m/s vs. 0.94 ± 0.15; P = 0.0001). There was also no significant relationship between SWS, gender, age, weight, and body mass index of patients (P > 0.05). Conclusion: The results showed that SWE can be used as a useful alternative for urorodynamic testing in the evaluation of NB (bladder dysfunction) in children.